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Cdk2 Inhibitor III - CAS 199986-75-9 - Calbiochem The Cdk2 Inhibitor III, also referenced under CAS 199986-75-9, controls the biological activity of Cdk2. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

Item no.

SAF-238803-5MG

CAS Number

[199986-75-9]

Unit

1 x 5 mg

Molecular formula

C20H28N6O3

Molecular weight

400,47

Price on request

Description

A cell-permeable purine analog that acts as a potent, selective, reversible, and ATP-competitive inhibitor of Cdk2 (IC50 = 0.5 µ,M for Cdk2/A and Cdk2/E, 4.2 µ,M for Cdk1/B, 215 µ,M for Cdk4/D1). Inhibits other kinases only at much higher concentrations (IC50 >1.25 mM for MAPK, PKA, and PKC). Shown to induce tumor cells growth arrest (IC50 = ~1.25-20 µ,M) in vitro and prevent neointima formation in vivo., A cell-permeable purine analog that acts as a potent, selective, reversible, and ATP-competitive inhibitor of Cdk2 (IC50 = 0.5 µ,M for Cdk2/A and Cdk2/E, 4.2 µ,M for Cdk1/B, 215 µ,M for Cdk4/D1). Inhibits other kinases only at much higher concentrations (IC50 >1.25 mM for MAPK, PKA, and PKC). Shown to induce tumor cells growth arrest (IC50 ~1.25-20 µ,M) in vitro and prevent neointima formation in vivo.

Structure formula

2( bis-(Hydroxyethyl)amino)-6-(4-methoxybenzylamino)-9-isopropyl-purine

Analyte	CAS Number	Concentration	Unit	Additional information	Method
2( bis-(Hydroxyethyl)amino)-6-(4-methoxybenzylamino)-9-isopropyl-purine	[199986-75-9]

Miscellaneous

Certificate of Analysis (specimen)

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Product data sheet

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