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Description

A selective inhibitor of MMP-13 (IC50 = 10 µ,M). Binds to the S1' pocket of MMP-13 with its morpholine ring adjacent to the catalytic zinc atom. Does not inhibit MMP-1, MMP-9, and TACE., A selective inhibitor of MMP-13 (IC50 = 10 µ,M) that does not appear to act by chelating Zn2+. Binds within the entire S1' pocket of MMP-13, docking with the morpholine ring adjacent to the catalytic zinc atom. Does not inhibit MMP-1, MMP-9, and TACE.

Structure formula

CL 82198 Hydrochloride

Contents

Miscellaneous

Certificate of Analysis (specimen)

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Product data sheet

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