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Description

An internally quenched, highly cathepsin K-selective, fluorogenic peptide substrate that is efficiently cleaved by CatK (kcat/Km = 0.426 µ,M⁻,¹, S⁻,¹,), but not by Cathepsins B/L/S/F/H/V., An internally quenched, highly cathepsin K-selective, fluorogenic peptide substrate that is efficiently cleaved by CatK (kcat/Km = 0.426 µ,M-1 S-1), but not by Cathepsins B/L/S/F/H/V. Studies using WT and CatK-/- mice reveal that the substrate is not cleaved by other proteolytic enzymes present in fibroblast lysates., An internally quenched, highly cathepsin K-selective, fluorogenic peptide substrate that is efficiently cleaved by CatK (kcat/Km = 0.426 µ,M-1 S-1), but not by Cathepsins B/L/S/F/H/V. Studies using WT and CatK-/- mice reveal that the substrate is not cleaved by other proteolytic enzymes present in fibroblast lysates. Emission Max: 420 NM, Excitation Max: 320 nM.