Item no.
SAF-178281-5MG
CAS Number
[74938-88-8]
Unit
1 x 5 mg
Shipment details
No Dangerous Good /not restricted
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Description
An alternative to DFP and PMSF. Specific irreversible inhibitor of trypsin-like serine proteases. Inhibits trypsin and thrombin in equimolar concentrations. Acts on C1r, C1s, Factor Xa and plasmin, requiring a 5- to 10-fold excess for complete irreversible inhibition. Inhibitory activity is approximately 1000-fold greater than that of PMSF. Stability is pH dependent: t1/2 = 20 min at pH 6.0, 6 min at pH 7.0, 1 millisecond at pH 8.0., Alternative to DFP and PMSF. An irreversible inhibitor of trypsin-like serine proteases. Inhibits trypsin and thrombin in equimolar concentration. Acts on C1r, C1s, Factor Xa, and plasmin, requiring a 5- to 10-fold excess for complete irreversible inhibition. Inhibitory activity is approximately 1000-fold greater than that of PMSF.
Structure formula
Contents
Miscellaneous
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