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AMPK Activator - CAS 849727-81-7 - Calbiochem The AMPK Activator, also referenced under CAS 849727-81-7, modulates the biological activity of AMPK. This small molecule/inhibitor is primarily used for Activators/Inducers applications.

Item no.

SAF-171256-5MG

CAS Number

[849727-81-7]

Unit

1 x 5 mg

Molecular formula

C22H21FO4

Molecular weight

368,4

Price on request

Description

A cell-permeable furancarboxylic acid compound that activates celular AMP-activated protein kinase (AMPK) activity by inhibiting mitochondrial complex I, and thus elevating intracellular AMP level. Shown to enhance glucose uptake in L6 myocytes (EC50 = 11.7 µ,M). Reduces blood glucose levels in ZDF rats in vivo (oral dose 30-100 mg/kg). Displays negligible cytotoxicity at pharmacological doses.

Structure formula

5-[3-[4-[2-(4-Fluorophenyl)ethoxy]phenyl]propyl]-2-furancarboxylic Acid

Analyte	CAS Number	Concentration	Unit	Additional information	Method
5-[3-[4-[2-(4-Fluorophenyl)ethoxy]phenyl]propyl]-2-furancarboxylic Acid	[849727-81-7]

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Certificate of Analysis (specimen)

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Product data sheet

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