Item no.
SAF-149101-1GM
CAS Number
[22059-21-8]
Unit
1 x 1 g
Molecular formula
C4H7NO2
Molecular weight
101,11
Shipment details
No Dangerous Good /not restricted
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Description
An agonist for the glycine modulatory site of the N-methyl-D-aspartate (NMDA) receptor complex. Mimics the effects of glycine on the NMDA receptor ion channel and blocks 3H-glycine binding to rat forebrain membrane (IC50 = 38 nM). Blocks NMDA-induced release of arachidonic acid (IC50 = 131 µ,M) in cerebellar granule cells. Reduces NMDA-induced cell death in hippocampal neurons., A potent and selective ligand for the glycine modulatory site of the N-methyl-D-aspartate (NMDA) receptor complex. Blocks 3H-glycine binding to rat forebrain membranes (IC50 = 38 nM).
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Structure formula
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