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Description
A cell permeable, reversible, and substrate competitive phosphatidylinositol ether analog that potently and selectively inhibits Akt (PKB) (IC50 of 5.0 µ,M). Moderately inhibits PI 3-K activity (IC50 = 83.0 µ,M). Also inhibits the growth of various cancer cell lines with IC50 values in the 1-10 µ,M range., A cell permeable, reversible, and substrate competitive phosphatidylinositol ether analog that potently and selectively inhibits Akt (PKB) (IC50 of 5.0 µ,M). Moderately inhibits PI 3-K activity (IC50 = 83.0 µ,M). Also inhibits the growth of various cancer cell lines with IC50 values in the 1 - 10 µ,M range.
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