Item no.
SAF-100073-10MG
Unit
1 x 10 mg
Molecular formula
C19H23NO4S
Molecular weight
361,46
Shipment details
No Dangerous Good
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Description
A cell-permeable, thiazolidinedione derivative that acts as a 15-hydroxyprostaglandin dehydrogenase (15-PGDH) inhibitor (IC50 = 25 nM). It is shown to increase PGE2 levels in IL-1beta-stimulated A549 cells, dose-dependently, in the range of 0-20 µ,M, and elicits cochlear blood flow (CBF) increase by 15% and 55% when applied intravenously to 250 g guinea pigs at 10 µ,g and 20 µ,g respectively.
Structure formula
Miscellaneous
Certificate of Analysis (specimen)
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Product data sheet
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