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Description

Neuropeptide found in high concentrations in the gut. When released from afferent nerves, causes a neurogenic inflammatory response, including mast cell degranulation. Induces Ca2+ mobilization. Reported to activate Goalpha, Gq/11alpha, and Gsalpha subunits in CHO cells via activation of substance P receptors. Also reported to induce superoxide production in neutrophils.

Structure formula

Substance P acetate salt hydrate

Contents

Miscellaneous

Certificate of Analysis (specimen)

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