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Beschreibung

A cell-permeable, reversible inhibitor of gamma-secretase. Inhibits the release of Abetax-40 (ED50 = 2.6 µ,M) and Abetax-42 (ED50 = 2.7 µ,M) in HEK293 cells stably transfected with Amyloid Precursor Protein Swedish mutants., A cell-permeable, reversible inhibitor of gamma-secretase. Equipotently inhibits the release of Abetax-40 (ED50 = 2.6 µ,M) and Abetax-42 (ED50 = 2.7 µ,M) in HEK293 cells stably transfected with the Amyloid Precursor Protein Swedish mutants.