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Beschreibung

Category: Aromatics, Miscellaneous Reagents /// Appearance: Clear Colorless Oil /// Application Notes: 3-(Trifluoromethyl)benzaldehyde is used as a reagent in the synthesis of 2,3-di- and 2,2,3-trisubstituted-3-methoxycarbonyl-gamma-butyrolactones as potent antitumor agents. Also used as a reagent in the synthesis of novel chalcone derivatives as hypoxia-inducible factor (HIF)-1 inhibitors. /// References: Le Floch, C., et al.: Eur. J. Med. Chem., 89, 654 (2015)| Wang, L., et al.: Eur. J. Med. Chem., 89, 88 (2015)