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Category: Aromatics, Pharmaceuticals, Intermediates and Fine Chemicals /// Appearance: Clear Colourless Oil /// Application Notes: 4-(Trifluoromethoxy)aniline is used in the synthesis of anticancer agents and antitumor medicaments. Also, its an intermediate in the production of labelled Riluzole (R510000), a neuroprotective agent. Modulates glutamatergic transmission. A glutamate release inhibitor. An anticonvulsant. /// References: Cilibrizzi, A., et al.: J. Med. Chem., 52, 5044 (2009), Verhaeghe, P., et al.: Bioorg. Med. Chem., 17, 4313 (2009), Chandregowda, V., et al.: Eur. J. Med. Chem., 44, 3046 (2009), Wahl, F., et al.: Eur. J. Pharmacol., 230, 209 (1993) Bensimon, G., et al.: N. Engl. J. Med., 330, 585 (1994)| Piras, S. et al.: Eur. j. Med. Chem., 75, 169 (2014)| Vyas, V. et al.: Eur. J. Med. Ch3m., 82, 385 (2014)|