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Category: Nucleotides, Bases and Related Reagents, Pharmaceuticals, Intermediates and Fine Chemicals, Phosphorylating and Phosphitylating Agents /// Appearance: White to Off-White Solid /// Application Notes: (S)-Tenofovir is an S-enatiomeric derivative of Tenofovir (T018500). (S)-Tenofovir displays virucidal activity against herpes, visna virus and retrovirus. The S enantiomer of Tenofovir (T018500) is less effective against HIV than their (R)-enantiomeric counterparts. /// References: Balzarini, J. et al: Biochem. Biophys. Res. Comm., 219, 337 (1996)| Balzarini, J. et al.: Antimicrob. Agents. Ch., 37, 332 (1993)| Thormar, H. et al.: Antimicorb. Agents. Ch., 37, 2540 (1993)