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Beschreibung

Category: Activators, Glycerols, Fatty Acid Derivatives and Lipids, Inhibitors, Protein Kinase Inhibitors and Activators /// Appearance: Off-White to Pale Beige Solid /// Application Notes: A putative lipid second messenger, found to inhibit cellular mobility of melanoma cells at very low concentrations with no toxic effects thereby making it a possible agent for prevention of tumor cell metastasis and inflammatory processes. It mobilizes intracellular calcium stores, decreases cellular cAMP, activates phospholipase D and does not inhibitprotein kinase C. /// References: Yeh, C., et al.: Am. J. Physiol., 296, H1193 (2009), Hagen, N., et al.: J. Biol. Chem., 284, 11346 (2009), Kuehnel, M., et al.: J. Cell Sci., 122, 499 (2009), XXX