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Beschreibung

Category: Amines, Aromatics, Inhibitors /// Appearance: White to Light Brown Solid /// Application Notes: Cytochrome P-459 inhibitor, blocks glibenclamide-sensitive K+ channels, inhibits neuronal nitric oxide synthetase, stimulates endothelial cell prostacyclin while inhibiting platelet thromboxane synthesis. /// References: Boeynaems, J.M., et al.: Prostaglandins Leukotrienes Med., 25, 123 (1986), Khan, S., et al.: Biochem. Pharmacol., 45, 439 (1993), Salvemini, D., et al.: Br. J. Pharmacol., 108, 162 (1993), Satoh, T., et al.: J. Clin. Invest., 91, 409 (1993)