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Beschreibung

Category: Aromatics, Pharmaceuticals, Intermediates and Fine Chemicals /// Application Notes: Ralfinamide mesylate is a mixed sodium and N-type calcium channel protein inhibitor. Inhibitory activity of Ralfinamide mesylate is voltage dependent, with higher potency towards inactivated channels. Ralfinamide mesylate is useful in preventing, alleviating and curing a wide range of pathologies, including pain, migraine, peripheral diseases, cardiovascular diseases, inflammatory processes affecting all body systems, disorders affecting skin and related tissues, disorders of the respiratory system, disorders of the immune and endocrinol. systems, gastrointestinal, urogenital, metabolic and seizure disorders. /// References: Bayes, M., et al.: Methods. Find. Exp. Clin. Pharmacol., 27, 411 (2005)| Pevarello, P., et al.: J. Med. Chem., 41, 579 (1998)| Bauer, M., et al.: Pharmacol., 85, 297 (2010)|