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Beschreibung

Category: Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates and Fine Chemicals /// Appearance: Off-White to Pale Beige Solid /// Application Notes: Pinocembrin is a flavanoid with antioxidant activity found in damiana, honey, and propolis. Recent studies show that Pinocembrin maybe be a therapeutic option in reducing cerebral ischemia/reperfusion injury as a result of its anti-oxidative and anti-apoptotic effects. Pinocembrin displayed neuroprotective effects in glutamate injury model partly by inhibiting p53 expression causing a lower Bax-Bcl-2 ratio and by inhibiting the release of cytochrome c. /// References: Zhao, J. et al.: J. Ethnopharmacol., 120, 387 (2008)| Liu, R. et al.: Brain Res., 1216, 104 (2008)| Gao, M. et al.: Eur. J. Pharmacol., 591, 73 (2008)|