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Beschreibung

Category: Amines, Aromatics, Inhibitors, Pharmaceuticals, Intermediates and Fine Chemicals, Sulfur and Selenium Compounds /// Appearance: Red-Brown Solid /// Application Notes: Histone deacetylase inhibitor. A cell-permeable, aromatic sulfonamide derivative with a hydroxamic acid group that potently inhibits mammalian HDAC by binding to the active site zinc. /// References: Ohtani, M., et al.: J. Med. Chem., 39, 2871 (1996), Dear, A.E., et al.: Biochem. Biophys. Acta, 1492, 15 (2000), Lavoie, R., et al.: Bioorg. Med. Chem. Lett., 11, 2847 (2001), XXX