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Beschreibung

Category: Anti-virals, Aromatcis, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates and Fine Chemicals /// Appearance: White Solid /// Application Notes: Novobiocin is an antibiotic that acts as an inhibitor of bacterial DNA gyrase and eukaryotic DNA topoisomerase. Studies show that Novobiocin is also an inhibitor of retrovirus RNA-dependent DNA-polymerase. Novobiocin is used in the production of positively supercoiled plasmid DNA. /// References: Cozarelli, N.R.: Science, 207, 953 (1980)| Sumiyoshi, Y. et al.: J. Gen. Virol., 64, 2329 (1983)| Lockshon, G. et al.: Nucleic Acids Res., 11, 2999 (1983)|