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Beschreibung

Category: Aromatics, Heterocycles /// Appearance: Pale Beige Solid /// Application Notes: 2,3-Naphthalic anhydride is used as a reagent to synthesize analogues of Thalidomide (T338850), an inhibitor of tumour necrosis factor that was once abandoned because it caused birth defects, but is currently used as an inhibitor of angiogenesis in patients with multiple myeloma. /// References: D?Amato, R., et al.: Proc. Nat. Acad. Sci., 91, 4082 (1994)| Ehrenpreis, E., et al.: Gastroenterology, 117, 1271 (1999)| Parma, T., et al.: Nat. Med., 5, 582 (1999)| Singhal, S., et al.: New Engl. J. Med., 341, 1565 (1999)