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Beschreibung

Category: Chiral Reagents, Metabolites and Impurities, Pharmaceuticals, Intermediates and Fine Chemicals /// Appearance: Off-White Solid /// Application Notes: An active carboxylate of Mevastatin (M340500). It is a competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase with hypocholesterolemic activity. It has been shown to be effective in reducing cholesterol synthesis in vivo, and thereby in lowering cholesterol levels in blood. /// References: Endo, A. et al.: Atheroscler. Supp., 5, 39 (2004)| Hosobuchi, M. et al.: J. Ferm. Bioeng., 76, 470 (1993)|