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Category: Amines, Miscellaneous Reagents /// Appearance: solid /// Application Notes: N-Methyltrifluoroacetamide is a useful synthetic intermediate. It is used to prepare electrophilic 11beta-aryl derivs. of estradiol as steroidal affinity labels of the estrogen receptor alpha. It is also used to synthesize amino substituted derivatives of 5'-amino-5'-deoxy-5'-noraristeromycin as antiviral agent. /// References: Aliau, S., et al.: J. Med. Chem., 43, 613 (2000)| Yang, M., et al.: Bioorg. Med. Chem., 13, 877 (2005)