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Category: Amines, Amino Acids and Derivatives, Chiral Reagents, Isotope Labelled Compounds, Pharmaceuticals, Intermediates and Fine Chemicals, Sulfur and Selenium Compounds /// Appearance: White Solid /// Application Notes: D-Methionine-d4 is labelled D-Methionine (M260550), an isomer of L-Methionine (M260440) which is a cytoprotectant against Cisplatin (C499500), an anticancer agent. D-Methionine is also used to prevent noise- and drug-induced hearing loss, as well as hair loss (all of which may also be caused by Cisplatin or aminoglycosides). /// References: Campbell, K., et al.: Hear. Res., 92, 103 (2007)| Cloven, N., et al.: Antican. Res., 20.6B, 4205 (1999)| Vuyyuri, S., et al.: Clin. Cancer Res., 14, 2161 (2008)