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Category: Amines, Aromatics, Metabolites and Impurities, NeuroChemicals Pharmaceuticals, Intermediates and Fine Chemicals /// Application Notes: The enatiomer of (+)-alpha-Methadol (M225860) and is more effective in binding to opiate receptors. The relative activities of (-)-alpha-Methadol and (+)-alpha-Methadol are reversed upon acetylation. A metabolite of (-)-alpha-Acetylmethadol (A186325). /// References: Horng, J.S. et al.: Res. Comm. Chem. Pathol. Pharmacol., 14, 621 (1976)| Casy, A.F. et al.: J. Med. Chem., 11, 601 (1968)| Ruemmler, R., et al.: Arzneim.-Forsch., 20, 281 (1970)|