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Beschreibung

Category: Amines, Aromatics, Chiral Reagents, Heterocycles, Inhibitors, Isotope Labelled Compounds, Metabolites and Impurities, Pharmceuticals, Intermediates and Fine Chemicals /// Application Notes: Linezolid N-Oxide-D3 is a labelled analogue of Linezolid N-oxide (L466530). Linezolid N-oxide is a derivative of Linezolid (L466500), an oxazolidinone antimicrobial that is used to treat infections against gram-positive bacteria, especially those that are drug-resistant (such as Vancomycin [HCl: V096500] resistant enterococci). Linezolid works by inhibiting bacterial protein synthesis. /// References: Dennis, L., et al.: Clin. Infect. Dis., 34, 1481 (2002)| Clemett, D. & Markham, A.: Drugs, 59, 815 (2000)| Gonzales, R., et al.: Lancet, 357, 1179 (2001)| Tsiodras, S., et al.: Lancet, 358, 207 (2001)