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Category: Amino Acids and Derivatives, Isotope Labelled Compounds, Pharmaceuticals, Intermediates and Fine Chemicals /// Appearance: White to Off-White Solid /// Application Notes: Labelled L-Leucine used as tracers to study human apolipoprotein B metabolism. L-Leucine is an essential amino acid. L-Leucine acts as a nutrient signal to stimulate protein synthesis. It has also activates the mammalian target of rapamycin kinase that regulates cell growth. /// References: Demant, T. et al.: Am. J. Physiol., 270, E1022 (1996)| Diraison, F. et al.: Am. J. Physiol., 277, E529 (1999)| Suryawan, A. et al.: J. Anim. Sci., 89, 2004 (2011)| Peyrollier, K. et al.: Biochem. J., 350, 361 (2000)|