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Beschreibung

Category: Pharmaceuticals, Intermediates and Fine Chemicals, Inhibitors, /// Appearance: Light Brown Solid /// Application Notes: (-)-Huperzine A-d5 (Major) is the labelled form of (-)-Huperzine A (H826000), a reversible alkaloid inhibitor of AChE which crosses the blood-brain barrier. A potential therapeutic agent for Alzheimer's disease. It reduces cell death induced by glutamate in primary cultures derived from forebrain, hippocampus, cortex and cerebellum of embryonic rat brain. /// References: Wang, Y.-E., et al.: Acta Pharmacol. Sin., 7, 110 (1986), Ved, H.S., et al.: Neuroreport, 8, 963 (1997)