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Beschreibung

Category: Amino Acids and Derivatives, Chiral Reagents, Heterocycles /// Appearance: Clear Colourless Oil /// Application Notes: (2S,4R)-4-Hydroxypyrrolidine-1,2-dicarboxylic Acid 1-tert-Butyl Ester 2-Methyl Ester is used in the synthesis of For-Met-Leu-Phe-OMe (fMLF-OMe) analogues based on Met residue replacement by 4-amino-proline scaffold. /// References: Freer, R., et al.: Biochemistry, 21, 257 (1982), Higgins, J., et al.: J. Med. Chem., 39, 1013 (1996), Cavicchioni, G., et al.| Bioorg. Chem., 34, 298 (2006), Selvatici, R., et al.: Eur. J. Pharmacol., 534, 1 (2006)