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Category: Aromatics, Inhibitors, Pharmaceuticals, Intermediates and Fine Chemicals /// Appearance: Clear Colourless to Orange Oil /// Application Notes: (+)-[6]-Gingerol is a bioactive compound found in ginger (Zingiber officinale) with antioxidant activity, which functions as an anti-inflammatory and antitumor agent. (+)-[6]-Gingerol down regulates proinflammatory cytokine release by macrophages. (+)-[6]-Gingerol has been shown to inhibit COX-2 expression by blocking the activation of p38 MAP kinase and NF-?B in phorbol ester-stimulated mouse skin. /// References: Aeschbach, R. et al.: Food Chem. Toxicol., 32, 31 (1994)| Tripathi, S. et al.: J. Surg. Res., 130, 318 (2006)| Kim, S.O., et al.: Oncogene 24, 2558 (2005)|