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Beschreibung

Category: Metabolites and Impurities, Nucleotides, Bases and Related Reagents, Pharmaceuticals, Intermediates and Fine Chemicals /// Appearance: White to Pale Yellow Solid /// Application Notes: 5-Fluoro Uracil is is an DNA/RNA synthesis inhibitor. It is used as a potent antitumor agent since it interrupts nucleotide synthetic by inhibiting thymidylate synthase. /// References: Longley, D., et al.: Nat. Rev. Cancer, 3, 330 (2003)| Bollag, W., et al.: Eur. J. Cancer, 16, 427 (1980)| Pinedo, H., et al.: J. Clin. Oncol., 6, 1653 (1988)| Ishikawa, T., et al.: Biochem. Pharmacol., 55, 1091 (1998)| Schuller, J., et al.: Cancer Chemother. Pharmacol., 45, 291 (2000)