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Category: Aliphatics, Amines, Miscellaneous Reagents /// Application Notes: 5-(N-Ethyl-N-2-hydroxyethylamino)-2-penthlamine is a useful synthetic intermediate in the synthesis of Hydroxy Chloroquine (H905300/H905305), a major metabolite of Chloroquine (C379965, diphosphate salt) which is a standard anti-malarial drug. /// References: Brocks, D., et al.: Clin. Pharmacokinet., 42, 1359 (2003)| Brocks, D., et al.: Clin. Pharmacokinet., 42, 1359 (2003)| Huang, S., et al.: Talanta, 64, 887 (2004)| Luthman, H., et al.: Nucleic Acids Res., 11, 1295 (1983)| Vezmar, M., et al.: Biochem. Pharmacol., 56, 733 (1998)| Krajewski, W.A., et al.: J. Biomol. Struct. Dyn., 16, 1097 (1999)