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Category: Metabolites and Impurities, Pharmaceuticals, Intermediates and Fine Chemicals /// Application Notes: 9-cis-5,6-Epoxy-5,6-dihydro-retinoic Acid is structurally similar to 9-cis-5,6-Epoxy retinol acetate (E589320) which is a derivative of Vitamin A (V676000), a fat-soluble compound that is known to exert a notably crucial influence on epithelial differentiation. Vitamin A and its synthetic derivatives are known to prevent chemical carcinogenesis. /// References: Fuchs, E. & Green, H.: Cell, 25, 617 (1981)| Sporn, M., et al.: Fed. Proc., 35, 1332 (1976)| Wolbach, S. & Howard, P.: J. Exp. Med., 42, 753 (1925)