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Appearance: Yellow Solid /// Application Notes: 2-(2,2-Diphenyl-1,3-benzodioxol-5-yl)-5,7-dihydroxy-3-(phenylmethoxy)-4H-1-benzopyran-4-one is an intermediate in the synthesis of Quercetin Dihydrate (Q509500), which is a lavonoid with anticancer activity. It is a mitochondrial ATPase and phosphodiesterase inhibitor. It Inhibits PI3-kinase activity and slightly inhibits PIP kinase activity. Quercetin has antiproliferative effects on cancer cell lines, reduces cancer cell growth via type II estrogen receptors, and arrests human leukemic T cells in late G1 phase of the cell cycle. /// References: Graziani, Y. et al.: J. Biochem., 135, 583 (1983)| Levy, J. et al.: Biochem. Biophys. Res. Comm., 123, 1227 (1984)| Wei, Y.Q. et al.: Cancer Res., 54, 4952 (1994)|