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Appearance: Yellow Solid /// Application Notes: 5,7-Dinitro-8-quinolinol is a useful synthetic intermediate. It has been reported that 5,7-dinitro-8-hydroxyquinoline derivatives exhibit higher antimycobacterial activity than ciprofloxacin (C482500) against M. abscessus and M. Smegmatis. In addition, 5,7-Dinitro-8-quinolinol has been employed to investigate structure-activity relationships of nitroxoline derivatives that may provide new insights on developing novel cathepsin B inhibitors. /// References: Cieslik, W., et al.: Med Chem. 11, 771 (2015)| Sosic, I., et al.: J. Med. Chem. 56, 521 (2013)