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Category: Aromatics, Metabolites and Impurities, Pharmaceuticals, Intermediates and Fine Chemicals /// Application Notes: 6,6'-Dimethoxy-2,2'-binaphthalene, can be used for the synthesis of novel classes of non-steroidal substrate mimetics, as inhibitors of human CYP17. It is also an impurity of Nabumetone (N200500), a non-steroidal anti-inflammatory drug, acting as anti-inflammatory agent. /// References: Kumpulainen, H., et al.: J. Med. Chem., 49, 1207 (2006)| Pinto-Bazurco, M. A. E., et al.: Bioorg. Med. Chem. Lett., 18, 267 (2008)|