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Category: Aromatics, Heterocycles, Pharmaceuticals, Intermediates and Fine Chemicals /// Appearance: Off-White to Pale Yellow Solid /// Application Notes: 3,4-Dihydro-7-hydroxyquinoline-2(1H)-one (Aripiprazole EP Impurity A) is an antitumor agent. Hydroxyindole analog inhibitor tyrosinase melanoma. This compound is also used in the preparation of aripiprazole (A771000). /// References: Bouchard, B., et al.: J. Exp. Med., 169, 2029 (1989), Kim, Y., et al.: J. Biol. Chem., 277, 16340 (2002), Cho, S., et al.: Bioorg. Med. Chem. Lett., 16, 2682 (2006), XXX