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Beschreibung

Category: Heterocycles, Inhibitors, Pharmaceuticals, Intermediates and Fine Chemicals, Steroids /// Appearance: White Solid /// Application Notes: Dihydro Finasteride (Finasteride EP Impurity A) is the reduced product of Finasteride (F342000): a mechanism-based inhibitor of human prostate and skin steroid 5alpha-reductase. It forms an enzyme-bound NADP-dihydrofinasteride adduct during this inhibitory process. /// References: Bull, H.G. et al.: Am. J. Chem. Soc., 118, 2359 (1996)| Liang, T. et al.: Endocrinol., 117, 571 (1985)| Ellsworth, K.P. et al.: J. Steroid Bioche. Mol. Biol., 66, 271 (1998)|