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Category: Chiral Reagents, Pharmaceuticals, Intermediates and Fine Chemicals, Steroids /// Application Notes: 20beta-Dihydrocortisol could be used as a potential non invasive diagnostic test of transmissible spongiform encephalopaties. 20beta-Dihydrocortisol is a metabolite of Cortisol (H714615), a steroid hormone, more specifically a glucocorticoid, produced by the zona fasciculata of the adrenal gland. Cortisol is released in response to stress and a low level of blood glucocorticoids. Its primary functions are to increase blood sugar through gluconeogenesis, suppress the immune system, and aid in fat, protein and carbohydrate metabolism. /// References: Schelcher, F., et. al.: Endocrinology, 140, 2422 (1999)| Phillipov, G., et. al.: J. Clin. Endocr. Metab., 81, 3855 (1996)| Vigore, L., et al.: Cancer Ther., 6, 699 (2008)|