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Category: Aromatics, Heterocycles, Pharmaceuticals, Intermediates and Fine Chemicals, Sulfur and Selenium Compounds /// Application Notes: 1-[(4,5-Dihydro-3-methyl-5-oxo-1-phenyl-1H-pyrazol-4-yl)methylamino]methanesulfonic Acid is an impurity of Dipyrone (D492860), a non-steroidal anti-inflammatory drug that, when coadministered with morphine, potentiates its antinociceptive action and delays the development of tolerance. /// References: Shleev, S.V., et al.: App. Biochem. Microbiol., 40, 140 (2004)| Shleev, S. V., et al.: App. Biochem. Biotechol., 111, 167 (2003)|