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Beschreibung

Category: Aromatics, Isotope Labelled Compounds, Mutagenesis Research Chemicals /// Appearance: Yellow Solid /// Application Notes: Labelled analogue of Dibenzo[a,i]pyrene, a polycyclic aromatic hydrocarbon (PAH) with potent carcinogenic activity. Dibenzo[a,i]pyrene was shown to induce DNA adduction, tumorigenicity as well as Ki-ras oncogene mutations in strain A/J mouse lung. Dibenzo[a,i]pyrene has been shown to be present in cigarette smoke condensate and in automobile exhaust gas in small quantities. /// References: Prahalad, A.K. et al.: Carcinogenesis, 18, 1955 (1997)| Wynder, E.L. et al.: Nature, 192, 1092 (1961)| Homburger, F. et al.: J. Nat. Cancer Inst., 44, 357 (1970)|