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Category: Miscellaneous Reagents /// Appearance: solid /// Application Notes: Copper(II) acetate is a versatile and cost-effective reagent that is used as a catalyst for N-monoalkylation of amino derivatives that are poor nucleophiles, and also for the synthesis of symmetrical 1,3-diynes. Copper(II) acetate is also used as a mild caustic in the medical field. /// References: Balaraman, K. & Kesavan, V.: Synthesis, 2010, 3461 (2010)| Martinez-Ascencio, A., et al.: Tetrahedron Lett., 51, 325 (2010)| Theophanides, T. & Anastassopoulou, J.: Crit. Rev. Oncol. Hematol., 42, 57 (2002)