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Category: Anti-virals, Non-nucleoside Reverse Transcriptase, Pharmaceuticals, Intermediates and Fine Chemicals, Inhibitors, /// Appearance: Off-White Solid /// Application Notes: Cobicistat is a HIV protease inhibitor and has been coadministered with low-dose ritonavir (R535000) as a pharmacoenhancer, significantly increasing their plasma concentrations. /// References: Von, H., Exp. Rev. Clin. Pharmacol., 5, 557 (2012)| Lepist, E.I., et al.: Antimicrob. Agent. Chemother., 56, 5409 (2012)| Orr, S.T.M., et al.: J. Med. Chem., 55, 4896 (2012)|