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Beschreibung

Category: Heterocycles, Intermediates, Pharmaceuticals, Intermediates and Fine Chemicals /// Appearance: Pale Yellow Solid /// Application Notes: (2R)-1-(Chloroacetyl)-2-pyrrolidinecarbonitrile, can be used in the synthesis of 1-[[(3-Hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine, and Vildagliptin (C363780), which are potent, selective, and orally bioavailable dipeptidyl peptidase IV Inhibitor with Antihyperglycemic properties, that might be used for the treatment of type 2 diabetes. /// References: Singh, S.K., et al.: Beil. J. Org. Chem., 4, 20 (2008)| Villhauer, E. B., et al.: J. Med. Chem., 46, 2774 (2003)|