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Beschreibung

Category: Aromatics, Heterocycles, Isotope Labelled Compounds, Metabolites and Impurities, Pharmaceuticals, Intermediates and Fine Chemicals /// Appearance: White to Off-White Solid /// Application Notes: (±)-Cetirizine-d4 Dihydrochloride is the labeled analogue of Cetirizine Dihydrochloride (C281100), a nonsedating type histamine H1-receptor antagonist. A major metabolite of Hydroxyzine. Pharmacological activity resides primarily in the (R)-isomer. Antihystaminic. /// References: De Vos, C., et al.: Ann. Allergy, 59, 278 (1987)| Juhlin, L., et al.: J. Allergy Clin. Immunol., 80, 599 (1987)| Fadel, R., et al.: Clin. Allergy, 17, 373 (1987)| Gengo, F.M., et al.: Clin. Pharmacol. Ther., 42, 265 (1987)