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Category: Aromatics, Miscellaneous Reagents /// Application Notes: iso-Butylbenzene is used as a reagent in the synthesis of 1,1-Bis(p-isobutylphenyl)ethane (B448875), an impurity in the synthesis of Ibuprofen (I140000). Also a reagent in the synthesis of quinoline-substituted furanone derivatives as selective falcipain-2 inhibitors. /// References: Busson, M., et al.: J. Int. Med Res., 14, 53 (1986)| Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993)| Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998)| Akhter, M., et al.: Med. Chem. Res., no vol., no pp. (2014)