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Category: Apoptosis, Aromatics, Heterocycles, Pharmaceuticals, Intermediates and Fine Chemicals /// Appearance: Off-White Solid /// Application Notes: Isotope labelled 4-Bromo-2-fluoro-N-methylbenzamide is an intermediate in the synthesis of MDV 3100 (M199800), is an androgen-receptor antagonist that blocks androgens from binding to the androgen receptor and prevents nuclear translocation and co-activator recruitment of the ligand-receptor complex. /// References: Jones, C.D.,e t al.: Bioorg. Med. Chem. Lett., 18, 6486 (2008)|