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Category: Aromatics /// Appearance: Clear Colourless Oil /// Application Notes: 4-Bromobenzotrifluoride is an aromatic compound that is used as a reagent to synthesize Bergenin (B318650), a compound that originates in Mallotus japonicus that exhibits hepatoprotective and antioxidant effects. 4-Bromobenzotrifluoride is also used as a reagent to prepare (±)-Preclamol, a partial dopamine D2 agonist that is used to treat Parkinson's disease. /// References: Lim, H., et al.: Pharmacology, 63, 71 (2001)| Parkan, K., et al.: Chem. Eur. J., 20, 4414 (2014)| Pirtosek, Z., et al.: Clin. Neuro., 16, 550 (1993)| Takahashi, H., et al.: Bioorg. Med. Chem., 11, 1781 (2003)| Vasdev, N., et al.: Synapse, 60, 314 (2006)