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Beschreibung

Category: Aromatics, Heterocycles, Inhibitors, Pharmaceuticals, Intermediates and Fine Chemicals, Sulfur and Selenium Compounds /// Appearance: Light Yellow Solid /// Application Notes: A potent and selective inhibitor of farnesyltransferase that induces mitochondrial apoptosis in chronic myeloid leukemia stem/progenitor cells, including CD34+38- cells, through activation of protein kinase Cbeta. /// References: Rose, W.C. et al.: Cancer Res., 61, 7507 (2001)| Tabernero, J. et al.: J. Clin. Oncol., 23, 2521 (2005)| Pellicano, F. et al.: Blood, 114, 4186 (2009)|