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Appearance: Clear Colorless to Pale Yellow Oil /// Application Notes: Bis(2-bromoethyl) Ether is used as a reagent in the synthesis of AZD 3147, a selective dual inhibitor of mTORC1 and mTORC2. Bis(2-bromoethyl) Ether is also used in the preparation of (2S)-2-Amino-3-(4-morpholin-4-ylphenyl)propanoic Acid (A618690), an impurity of Melphalan (M216900) which is an antineoplastic. /// References: Pike, K.G., et al.: J. Med. Chem., 58, 2326 (2015)| Ross, W.C.J., et al.: Biochem. Pharmacol., 13, 969 (1964)| Donelli, M.G., et al.: J. Pharm. Pharmacol., 18, 760 (1966)| Furner, R.L., et al.: Cancer Treat. Rep., 64, 559 (1980)