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Beschreibung

Category: Aromatics, Heterocycles, Inhibitors, Isotope Labelled Compounds, Sulfur and Selenium Compounds /// Application Notes: Benzo[b]thien-2-yl ketone-D10 is a labelled analogue of Benzo[b]thien-2-yl ketone (B207710). Benzo[b]thien-2-yl ketone is an impurity of Zileuton (Z420000), an inhibitor of 5-lipoxygenase that is used to treat patients with asthma. Benzo[b]thien-2-yl ketone is used as a reagent to synthesize Bis(1H-2-indolyl)methanone, compounds that inhibit the activity of growth factor receptor kinase. Benzo[b]thien-2-yl ketone is also used as a reagent to prepare annulated oligothiophenes, compounds that are used in organic light-emitting devides (OLEDs). /// References: Israel, E., et al.: JAMA, 275, 931 (1996)| Mahboobi, S., et al.: J. Med. Chem., 45, 1002 (2002)| Mitschke, U. & B?uerle, P.: J. Chem. Soc. Perk. Trans., 1, 740 (2001)| Nenajdenko, V., et al.: Russ. Chem. Bull., 61, 1456 (2012)